IPOX® Health Innovation Index (IPHI)
The IPOX® Health Innovation Index (IPHI) is a diverse and dynamic portfolio consisting of leading companies in the healthcare and biotechnology sectors, focusing on recent listings (e.g. IPOs, Spin-Offs and SPACs) as well as acquirers of biotech innovation (“IPO M&As”). Using this strategy, the index captures the performance of both established and emerging players focused on innovative solutions, novel therapies, and cutting-edge medical technologies.
Key Features:
Innovation Focus: Targets companies at the forefront of healthcare advancements, from novel drug development to transformative medical technologies and services.
Diverse Exposure: Includes a mix of established large-cap pharmaceutical and healthcare leaders alongside dynamic small and mid-cap innovators.
Global Reach: Represents health innovation across key global markets, including North America, Europe, and Asia.
Rules-Based Methodology: Employs IPOX's proprietary technology to identify and weight constituents based on market cap, liquidity, and strategic M&A activity, rebalancing quarterly.
Health Innovation Themes in Focus
Global Leaders & Strategic Acquirers
The index is anchored by established global healthcare giants that provide stability and often act as strategic acquirers of innovation. These include major pharmaceutical companies like GSK, AbbVie, Amgen, and Roche, alongside diversified healthcare leaders such as Abbott Laboratories and Thermo Fisher Scientific. These companies drive significant advancements through their extensive R&D pipelines and strategic integration of emerging technologies.
Biotech Frontiers: Advancing Novel Therapies
A core component of the index represents the cutting edge of biotechnology, featuring companies developing novel therapies for unmet medical needs. Examples include Vertex Pharmaceuticals, a leader in cystic fibrosis and cell/gene therapies; BridgeBio Pharma, focused on genetic diseases; Krystal Biotech, developing gene therapies for rare skin diseases; Legend Biotech, advancing cell therapies in oncology; and SpringWorks Therapeutics, targeting rare tumors and hematologic cancers. This segment captures the high-growth potential of breakthroughs in biological science.
MedTech & Health Services Innovation
Beyond therapeutics, the index captures innovation in medical technology, diagnostics, and healthcare services. This includes Stryker, a global leader in medical devices and equipment; diagnostic and imaging powerhouses Siemens Healthineers and GE Healthcare; health savings administrator HealthEquity; physician networking platform Doximity; and healthcare payments provider Waystar Holding. These companies are transforming how healthcare is delivered, managed, and accessed.
The IPOX® Health Innovation Index offers investors a unique way to access the broad spectrum of healthcare innovation, from foundational large-cap players to the next generation of biotech and medtech leaders. Its dynamic approach aims to capture the companies shaping the future of global health.
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