Corporate action in the IPOX 100 US Index (IPXO) RXDX/U

This is to notify the following pending corporate action in the IPOX 100 U.S. index (IPXO).

PROMETHEUS BIOSCIENCES INC (RXDX UW) will be acquired by MERCK & CO. INC. (MRK UN).

Treatment

PROMETHEUS BIOSCIENCES INC will be replaced by UNITY SOFTWARE INC (U UN Equity/U.N/US91332U1016) in a weight-neutral transaction. Effective Date (OPEN): 06/21/2023

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